Handsheet Coated by Polyvinyl Acetate as a Drug Release System

Mechanisms controlling drug release from coated pellets.

Since the use of PEG-coated pellets for the first oral sustainedrelease formulation in 1952, coated pellets have been used extensively to control the drug release kinetics. The term “pellet” has been used interchangeably with other terms, such as bead, sphere, granule, and particle. A large number of drug products have been available to patients. Despite extensive use of the coated pellets, the...

AN EXPLORATORY INVESTIGATION OF VISCOELASTIC NANOINDENTATION ON POLYVINYL ACETATE By

drug release modeling from a novel temperature-responsive polymeric system

nowadays, environment-sensitive smart drug delivery systems have found diverse applications in pharmaceutical science and technology. these systems can respond to the environment stimuli such as temperature, pressure, ph, light, electrical and magnetical fields and etc. they can release the proper amount of drug in human body. among these systems, special attention and much research works have ...

Design and evaluation of hydrophobic coated buoyant core as floating drug delivery system for sustained release of cisapride

An inert hydrophobic buoyant coated-core was developed as floating drug delivery system (FDDS) for sustained release of cisapride using direct compression technology. Core contained low density, porous ethyl cellulose, which was coated with an impermeable, insoluble hydrophobic coating polymer such as rosin. It was further seal coated with low viscosity hydroxypropyl methyl cellulose (HPMC E15)...

Flow behaviour of polyvinyl alcohol (PVOH) modified blends of polyvinyl acetate (PVAc)/natural rubber (NR) latexes

During compounding processes, polymer latexes are mixed with various colloidal systems (in particular, PVOH) or surface-active agents to modify the flow behaviour in order to suit the manufacturing process. In this study, the flow behaviour of aqueous dispersed PVAc, NR and different mixed dispersions were investigated both in the absence and presence of PVOH as flow modifier, using an Ostwald ...